Vitamin D Derivatives
Vitamin D derivatives are treatments that are likely to be the first prescribed to you if you have plaque psoriasis. Three topical vitamin D derivatives are currently available in cream, lotion or ointment preparations. Your healthcare team will prescribe the vitamin D derivative treatment best suited to you, based on the severity and type of your psoriasis.
Vitamin D derivatives are often used in combination with other treatments such as topical steroids or phototherapy. This helps to increase the effectiveness of psoriasis treatment and may reduce side effects as it may be possible to reduce the dose or frequency of other treatments.
How do they work?
Vitamin D derivatives help to bring your skin cell growth back to normal.
When are they used?
Vitamin D derivatives are used to treat plaque psoriasis.
How are they administered?
Treatment is applied directly to the skin once or twice a day depending on the product. The finger tip unit (FTU) can be used to judge how much vitamin D derivative is needed.
.jpg)
One FTU is the length between the tip of your finger and first joint. Your healthcare team will advise on how often to apply your treatment.
Tips for applying vitamin D derivatives
- If you are also using an emollient, apply your emollient at least 30 minutes before you apply your vitamin D derivative treatment
- Wash your hands before and after applying
There may be limits on the amount of vitamin D derivative treatment you should be using each week. This depends on which type of vitamin D derivative you are using. Your healthcare team will advise you on the correct amount when they prescribe it for you.
Advantages and disadvantages
Vitamin D derivatives may take a little longer to work than topical steroids, but they can be used for a longer period of time than topical steroids. Some vitamin D derivatives can be used on easily irritated areas such as your face and sensitive areas.
Applying a vitamin D derivative may cause skin irritation for a short while. Other side effects include skin rash, redness and itchy skin. The amount of vitamin D derivative you use may be limited because of certain side effects associated with this type of medication. Your healthcare team will advise you on the correct amount to use.
If you have any questions about vitamin D derivatives, you may want to discuss them with a member of your healthcare team.